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Ketoacyl coa thiolase

http://www.sh-haling.com/haling-Article-3323539/ Web9 jan. 2024 · This paper reports that the human peroxisomal 3-ketoacyl-CoA thiolase expression shows three transcripts: Tr1 (1705 bp), Tr2 (1375 bp) and Tr3 (1782 bp). Their highest expression is observed in the human liver and at a lesser extent in hepatic-derived HepG2 cells. The intestine and blood and endothelial cells show lower expression.

Arabidopsis 3-ketoacyl-CoA thiolase-2 (KAT2), an enzyme of fatty …

WebResponsible for the thiolytic cleavage of straight chain 3-keto fatty acyl-CoAs (3-oxoacyl-CoAs) ( PubMed: 10064897, PubMed: 2882519 ). Plays an important role in fatty acid … rachael ray show going off the air https://healinghisway.net

Requirement for 3‐ketoacyl‐CoA thiolase‐2 in peroxisome …

Web12 mrt. 2024 · The tripartite complex is found in almost all archaeal genomes and in some bacterial ones. In addition, the DUF35 proteins are also important for polyhydroxyalkanoate (PHA) biosynthesis, most probably by functioning as a scaffold protein that connects thiolase with 3-ketoacyl-CoA reductase. Web1 okt. 1997 · We describe the distribution in human tissues of three enzymes of ketone body utilization: succinyl-CoA:3-ketoacid CoA transferase (SCOT), mitochondrial acetoacetyl-CoA thiolase (T2), and ... Web28 aug. 2007 · Abstract. The enzyme 3-ketoacyl-CoA thiolase (KAT) (EC 2.3.1.16) catalyses a key step in fatty acid β-oxidation. In Arabidopsis thaliana, expression of the KAT2 gene is known to be required for the efficient mobilization of triacylglycerol during germination and seedling establishment. Here, data from the Arabidopsis kat2-1 mutant … shoe repair downtown ottawa

Cloning and stress-respondent transcription of 3-ketoacyl-CoA …

Category:Medium-Chain Ketoacyl-CoA Thiolase Deficiency - Baby Health

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Ketoacyl coa thiolase

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Web1 mrt. 2016 · Kiema TR, Harijan RK, Strozyk M, Fukao T, Alexson SE, Wierenga RK: The crystal structure of human mitochondrial 3-ketoacyl-CoA thiolase (T1): insight into the reaction mechanism of its thiolase and thioesterase activities. Acta Crystallogr D Biol Crystallogr. 2014 Dec 1;70(Pt 12):3212-25. doi: 10.1107/S1399004714023827. Epub … Web3-ketoacyl-CoA synthase 1 Gene KCS1 Status UniProtKB reviewed (Swiss-Prot) Organism Arabidopsis thaliana (Mouse-ear cress) Amino acids 528 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Download Add a publication Entry feedback Function

Ketoacyl coa thiolase

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Web30 aug. 2005 · PTHR43853:SF8 3-KETOACYL-COA THIOLASE, PEROXISOMAL 1 hit; PROSITE. View protein in PROSITE; PS00098 THIOLASE_1 1 hit; PS00737 … WebTrifunctional enzyme subunit beta, mitochondrial (TP-beta) also known as 3-ketoacyl-CoA thiolase, acetyl-CoA acyltransferase, or beta-ketothiolase is an enzyme that in …

Web(1997) A second isoform of 3-ketoacyl-CoA thiolase found in Caenorhabditis elegans, which is similar to sterol carrier protein-x but lacks the sequence of sterol carrier protein-2. Eur. J. Biochem. 245: 252 – 259. Web19 dec. 2008 · Medium-chain ketoacyl-CoA thiolase deficiency is a disorder associated with vomiting, dehydration, metabolic acidosis, liver dysfunction, and rhabdomyolysis. …

WebArabidopsis 3-ketoacyl-CoA thiolase-2 (KAT2), an enzyme of fatty acid β-oxidation, is involved in ABA signal transduction. The phytohormone ABA plays an important role in … Web19 dec. 2008 · Medium-chain ketoacyl-CoA thiolase deficiency is a disorder associated with vomiting, dehydration, metabolic acidosis, liver dysfunction, and rhabdomyolysis. This disorder can lead to breathing problems, convulsions, coma, and death. The cause of medium-chain ketoacyl-CoA thiolase deficiency is unknown. Names and Codes

WebAbstract. Peroxisomal 3-ketoacyl-CoA thiolase B (Thb) catalyzes the final step in the peroxisomal β-oxidation of straight-chain acyl-CoAs and is under the transcription control …

WebHADHA is an 82.9 kDa protein composed of 763 amino acids. [6] [7] The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. The genes of the alpha and beta subunits of the mitochondrial trifunctional ... shoe repair doylestownWeb25 sep. 2012 · Thiolases are crucial for both synthesis and catabolism of fatty acids, which catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA. The thiolase of a unicellular alga Isochrysis galbana (IgKAT) has not been identified yet. In this study, a full-length cDNA of 3-ketoacyl-CoA thiolase gene (IgKAT) was isolated … rachael ray show giveaway todayWebOur aim was to determine whether treatment with the antianginal agent trimetazidine, which inhibits fatty acid oxidation in the heart secondary to inhibition of 3-ketoacyl-CoA … shoe repair downtown pittsburghWeb3-Ketoacyl-Coa Thiolase, Peroxisomal: 501: Polysphondylium pallidum: D3BPS6: PPL_09970: 418: 1.0: 1.0: Acetyl-Coa C-Acyltransferase: Group ID Species Protein Gene Name Bitscore info_outline Inparalog Score info_outline Seed Score info_outline Description View Group; 475: Homo sapiens: P09110: ACAA1: 324: 1.0: 0.994: shoe repair downtown sacramentoWeb3 apr. 2024 · Promiscuity of the last enzyme of the pathway, medium-chain ketoacyl-CoA thiolase (MCKAT), was both necessary and sufficient to elicit the flux decline. Subsequently, Metabolic Control Analysis revealed that MCKAT had insufficient capacity to cope with high substrate influx. shoe repair downtown portlandWebMedium-chain ketoacyl-CoA thiolase (MCKAT) deficiency is a condition that prevents the body from breaking down certain fats and turning them into energy. If the body does not … rachael ray show january 12 2022Web17 jul. 2024 · Interestingly, site-directed mutagenesis of BktB revealed that the catalytic triad Cys–His–Cys involved in the native ketoacyl-CoA thiolase activity is also required for the non-native PKT ... rachael ray show greek stuffed peppers