WebPlasma concentrations of ketamine were measured in this study and ranged from undetectable to 30 ng/mL, as against a serum threshold level of 2000 ng/mL for induction of psychoactive effects, indicating essentially negligible potential for systemic side effects including the feared psychotomimetic adverse effects.16 17 More broadly, a systematic … Web{{configCtrl2.metaDescription()}}
Ketamine BJA Education Oxford Academic
Web18 dec. 2013 · Moreover, 6-h exposures to equipotent doses of 7.4%–8.0% desflurane, 0.75%–2.0% isoflurane, ... In addition, in both studies, ketamine-induced neuronal apoptosis was accompanied by a significant decrease in mitochondrial membrane potential and an increase in pro-apoptotic protein release from mitochondria into cytosol, ... gather up chrome extension
Alternatives to Rapid Sequence Intubation: Contemporary …
WebLow doses of ketamine are those that are not intended to induce moderate to deep sedation or general anesthesia. Clinicians must be vigilant for the effects of ... be induced with a range of 1-4.5 mg/kg (average dose 2 mg/kg), … IV: 1. Induction: 1 to 4.5 mg/kg IV; alternatively, 1 to 2 mg/kg IV at a rate of 0.5 mg/kg/min; (2 mg/kg dose provides 5 to 10 minutes of surgical anesthesia within 30 seconds) 2. Maintenance: The maintenance dose should be adjusted according to the patient's anesthetic needs and whether an additional … Meer weergeven Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Medical Disclaimer Meer weergeven Safety and efficacy have not been established in patients younger than 16 years. Consult WARNINGS section for additional precautions. Meer weergeven Administration advice: 1. This drug should be administered slowly (over a period of 60 seconds). More rapid administration may result in … Meer weergeven WebINDUCTION AGENTS Ketamine Dose: 1.5 mg/kg IV (4mg/kg IM) Onset: 60-90 sec Duration: 10-20 min Use: any RSI, especially if hemodynamically unstable (OK in TBI, does not increase ICP despite traditional dogma) or … gather up extension