Icbp gwas
WebbWeperformedgenome-wideassociationstudies(GWAS)ofblood pressuretraits(= 458,577Europeans)underanadditivegenetic n model 17 (SupplementaryTable 1a).Followinglinkagedisequilib- Webb17 nov. 2024 · CRGGH published the first GWAS for blood pressure (BP) in AA using data from the Howard University Family Study, a population-based sample of ~2,000 related and unrelated African Americans from the Washington, DC area that was collected by Dr. Rotimi and his group. GWAS loci in 5 genes reaching genome-wide significance for BP …
Icbp gwas
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Webb15 apr. 2024 · This study relied on de-identified summary-level data that have been made publicly available (the International Consortium for Blood Pressure [ICBP] GWAS and the International Genomics of Alzheimer's Project [IGAP] GWAS) and on the patient-level UKBB phenotypic and genetic data; ethical approval was obtained in all original studies … WebbThe MRC Integrative Epidemiology Unit at the University of Bristol (IEU) conducts some of the UK’s most advanced population health science research. It uses genetics, population data and experimental interventions to look for the underlying causes of chronic disease. Researchers at the MRC IEU have created a range of openly available software ...
Webb1 jan. 2024 · Large-Scale European GWAS Metaanalyses. The first large-scale metaanalyses of GWAS results for SBP, DBP, and case/control hypertension were published in 2009 [11], [12].Two consortia analyzed approximately 2.5 M SNPs in large numbers of individuals (~30,000) of European ancestry and followed up their top ten … Webb12 mars 2024 · International Consortium for Blood Pressure (ICBP) Coronary heart disease: Coronary Artery Disease Genome-wide Replication and Meta-analysis (CARDIOGRAM) ... (ICBP) GWAS consortium for 26 variants that were robustly associated with SBP at genome-wide statistical significance levels.
Webb13 okt. 2011 · 近日两项大型的全基因组关联研究（GWAS）发现了多个影响血压性状的遗传位点，包括收缩压和舒张压、脉压和平均动脉压。 血压是一种可遗传的性状，它受到体内一些通路以及外界环境因素的影响。目前全球超过10亿人患有高血压，即收缩压高于140mmHg，或舒张压高于90mmHg。 Webb3 nov. 2024 · The GWAS of the Electronic Medical Records and Genomics (eMERGE) network included 1,106 NAFLD cases and 8,571 controls identified only 1 NAFLD susceptibility locus ( PNPLA3 ). The NAFLD GWAS of the UK Biobank included 1,664 NAFLD cases and 400,055 controls identified only 2 regions robustly associated with …
Webb1 juni 2011 · Abstract The prevalence of hypertension in African Americans (AAs) is higher than in other US groups; yet, few have performed genome-wide association studies (GWASs) in AA. Among people of European descent, GWASs have identified genetic variants at 13 loci that are associated with blood pressure. It is unknown if these …
http://neuro.dxy.cn/article/13204 boxwood leaves turn yellowWebb12 sep. 2011 · Two published papers by The International Consortium for Blood Pressure Genome-Wide Association Studies (ICBP-GWAS) report on the identification of new gene loci associated with hypertension and... boxwood leaves graphicWebb5 apr. 2024 · 该生物数据库是一个试点项目，目的是将英国电子医疗记录中的数据与 遗传 数据联系起来，从而建立一个更全的英国国民健康保险制度（National Health Service）生物库。 它是目前世界上已建成人类遗传队列生物样本库中规模最大的。 其收集了来自英国各地，年龄在40岁至69岁之间，大约50万志愿者的疾病和生活方式信息及基因型数据。 … boxwood letter wreathgutter cleaning johnstown paWebbbGWAS is an R-package to perform a Bayesian GWAS (Genome Wide Association Study), using summary statistics from a conventional GWAS as input. The aim of the approach is to increase power by leveraging … gutter cleaning irelandWebbThe ICBP consortium is an international effort to investigate blood-pressure genetics. The consortium was formed by two parent consortia, the CHARGE-BP consortium (Cohorts … gutter cleaning kamloops bcWebb9 juli 2024 · This study comprises a fixed-effects inverse variance weighted meta-analysis of genotyped and imputed SNPs from the International Consortium for Blood Pressure (ICBP) and the UK Biobank. The ICBP GWAS data consists of 77 cohorts for 299,024 individuals of European ancestry genotyped with various arrays and imputed to either … gutter cleaning jersey