WebSep 1, 2024 · This G6PD CPIC guideline differs from others in that there is a large number of drugs carrying regulatory or literature warnings for use in patients with G6PD … WebKeywords: CPIC, G6PD, glucose-6-phosphate dehydrogenase deficiency, pharmacogenetics, pharmacogenomics, rasburicase, primaquine Conflicts of Interest: …
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WebG6PD deficiency is a genetic disorder that most often affects males. It happens when the body doesn't have enough of an enzyme called glucose-6-phosphate dehydrogenase … WebJan 25, 2024 · DPWG and CPIC have a main focus on pharmacotherapeutic recommendations for a large number of drugs in combination with a patient's genotype or predicted phenotype. DPWG, CPNDS and RNPGx also recommend on performing genetic testing in daily clinical practice, with RNPGx even describing specific clinical settings or … landasan kegiatan studi banding
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WebCPIC GuIdelInes WHO Class)).13–15 Most of the genetic variants in G6PD are missense variants resulting in single amino acid substitutions; a few are in-frame deletions of one … WebMay 2, 2014 · Glucose-6-phosphate dehydrogenase (G6PD) deficiency is associated with development of acute hemolytic anemia (AHA) induced by a number of drugs. We provide guidance as to which G6PD genotypes are associated with G6PD deficiency in males and females. Rasburicase is contraindicated in G6PD-deficient patients due to the risk of … WebRasburicase is a recombinant urate oxidase that catalyzes the oxidation of uric acid into allantoin, a more soluble metabolite. Within hours of intravenous administration, rasburicase directly reduces serum uric acid concentrations, making it an essential therapy for the prevention and treatment of hyperuricemia in patients with tumor lysis syndrome (TLS). landasan iptek adalah