Outpatient: 1 mg/kg subcutaneously every 12 hours Inpatient: 1 mg/kg subcutaneously every 12 hours or 1.5 mg/kg subcutaneously once a day at the same time every day. Duration of therapy: At least 5 days and until a therapeutic oral anticoagulant effect has been achieved (INR 2 to 3). Average … See more 40 mg subcutaneously once a day Duration of therapy: Usually 6 to 11 days; up to 14 days has been well tolerated in clinical trials. … See more 40 mg subcutaneously once a day with the initial dose given 2 hours prior to surgery Duration of therapy: Usually 7 to 10 days; up to 12 days has been well tolerated in clinical trials. Use:Prophylaxis of deep vein thrombosis (DVT) in … See more Unstable Angina and Non Q Wave Myocardial Infarction: 1 mg/kg subcutaneously every 12 hours in conjunction with oral … See more 75 Years or Older: Initial dose: 0.75 mg/kg subcutaneously every 12 hours (maximum 75 mg for first two doses only, followed by 0.75 mg/kg for the remaining doses). Comments: 1. Do not use an initial IV bolus. 2. No dose … See more WebThe maximum dose of enoxaparin should be 150 mg SC Q 12 h. For a patient receiving a dose of enoxaparin of 130 mg to 150 mg (i.e., patient weight 130 kg to 150 kg or greater), the low molecular weight heparin assay may be a useful monitoring tool.
Drug dosing in the critically ill obese patient: a focus on …
WebJan 24, 2024 · Enoxaparin (Lovenox) is an injectable drug used to prevent and treat blood clots. Learn about side effects, warnings, dosage, and more. ... 1 mg per kg of body weight injected every 12 hours while ... WebApr 3, 2024 · 1 mg enoxaparin has 100 units of anti-factor Xa activity (e.g., 40 mg enoxaparin = 4,000 units of anti-Xa). ... Correcting the dose for weight increases the likelihood of obtaining target drug levels. (iii) Many protocols involve a variety of arbitrary cutoffs and tiers based on weight and body mass index. Using a single formula is … honeywell prowatch user manual
Appendix 3: Weight based Dosing for VTE …
WebAug 11, 2024 · In overweight patients, weight-based enoxaparin dosing, using total body weight, has been reported as effective at once-daily doses of 0.4 and 0.5 mg/kg, 1, 3 as well as with doses of 0.5 mg/kg every 12 h. 4, 5 In patients with a body mass index (BMI) ≥30 kg/m 2, fixed-dose regimens of 40 mg enoxaparin twice daily have been shown to … WebEnoxaparin: Preterm neonates: 2 mg/kg/dose subQ every 12 hours. Term neonates: 1.5 to 1.7 mg/kg/dose subQ every 12 hours. Infants ≥2 months, children, ... LMWH: low molecular weight heparin; subQ: subcutaneously. * Dose adjustment is necessary for patients with kidney impairment. More frequent monitoring of anti-factor Xa levels may also be ... WebFor thromboprophylaxis with LMWH in nonbariatric surgery and in medical inpatients ( n = 8 studies), enoxaparin 0.5 mg/kg once or twice daily or tinzaparin 75 IU/kg once daily may be considered in obese patients. For treatment with LMWH ( n = 18 studies), a reduced weight-based dose of enoxaparin 0.8 mg/kg twice daily should be considered in ... honeywell purifier