WebApr 25, 2024 · The most well-known type of circRNA interaction is with microRNAs (miRNAs). Individual circRNAs can harbor multiple miRNA binding sites to act as a “sponge” and inhibit activity of one or multiple miRNAs. ... We also summarize the mechanisms by which circRNAs function, including RNA and protein interactions, and we describe the … WebDec 14, 2024 · CircRNA-protein interactions make changes to proteins and thus make a difference in life processes, which sparks our interest in devising novel clinical …
Genes Free Full-Text Integration Analysis of …
WebFeb 10, 2024 · CircRNAs bind and sequester specific proteins to appropriate subcellular positions, and they participate in modulating certain protein-protein … WebCircular RNAs (circRNAs) are a recently discovered class of RNAs derived from protein-coding genes that have important biological and pathological roles. They are formed through backsplicing during co-transcriptional alternative splicing; however, the unified mechanism that accounts for backsplicing decisions remains unclear. pascal lietard
Mapping CircRNA–miRNA–mRNA regulatory axis …
WebAug 8, 2024 · Methods to assess circRNA–protein interactions are based on the isolation of a circRNA (RNA-centric) or a protein (protein-centric), followed by the analysis of the interaction partners of the ... WebApr 12, 2024 · So far, most reported circRNAs promote the development and progression of RCC through circRNA-microRNA-mRNA interaction networks [ 17 ]. The ability of circRNAs to act as scaffolds to... WebAug 10, 2024 · RNA pull-down and immunoprecipitation (RIP) assays were used to analyze the interaction between circRNA_102231 and IRTKS. CircRNA_102231 expression was significantly upregulated in GC tissue and plasma samples, which can be used as a biomarker for GC diagnosis and prognosis. pascal lienert fhnw